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Scientific Research

AmnioFix® & EpiFix®

Koob TJ, Rennert R, Zabek N, Massee M, Lim JJ, Temenoff JS, Li WW, Gurtner G. Biological properties of dehydrated human amnion/chorion composite graft: implications for chronic wound healing. Int Wound J. 2013 Oct;10(5):493-500.

Koob TJ, Lim JJ, Massee M, Zabek N, Rennert R, Gurtner G, Li WW. Angiogenic properties of dehydrated human amnion/chorion allografts: therapeutic potential for soft tissue repair and regeneration. Vasc Cell. 2014 May 1;6:10.

Koob TJ, Lim JJ, Massee M, Zabek N, Denozière G. Properties of dehydrated human amnion/chorion composite grafts: Implications for wound repair and soft tissue regeneration. J Biomed Mater Res B Appl Biomater. 2014 Aug;102(6):1353-62.

Maan ZN, Rennert RC, Koob TJ, Januszyk M, Li WW, Gurtner GC. Cell recruitment by amnion chorion grafts promotes neovascularization. J Surg Res. 2015 Feb; 193(2):953-62.

Koob TJ, Lim JJ, Zabek N, Massee M. Cytokines in single layer amnion allografts compared to multilayer amnion/chorion allografts for wound healing. J Biomed Mater Res B Appl Biomater. 2015 Jul;103(5):1133-40.

Massee M, Chinn K, Lei J, Lim JJ, Young CS, Koob TJ. Dehydrated human amnion/chorion membrane regulates stem cell activity in vitro. J Biomed Mater Res B Appl Biomater. 2015 Jul 14. doi:10.1002/jbm.b.33478.

Massee M, Chinn K, Lim JJ, Godwin L, Young CS, Koob TJ. Type I and II Diabetic Adipose-Derived Stem Cells Respond In Vitro to Dehydrated Human Amnion/Chorion Membrane Allograft Treatment by Increasing Proliferation, Migration, and Altering Cytokine Secretion. Adv in Wound Care. 2015 Aug 26. doi:10.1089/wound.2015.0661.

Lei J, Priddy LB, Lim JJ, Massee M, Koob TJ. Identification of Extracellular Matrix Components and Biological Factors in Micronized Dehydrated Human Amnion/Chorion Membrane. Adv Wound Care. 2016 Sep. doi:10.1089/wound.2016.0699.

Lim JJ, Koob TJ. Placental Cells and Tissues: The Transformative Rise in Advanced Wound Care. In: Fonseca C, Editor. Worldwide Wound Healing – Innovation in Natural and Conventional Methods. Rijeka, Croatia: InTech, 2016. 121-151.

Lim JJ, Fonger J, Koob TJ. Dehydrated Human Amnion/Chorion Membrane Allograft Promotes Cardiac Repair Following Myocardial Infarction. J Cardiol & Cardiovasc Ther 2017; 2(5): 555599.

Lei J, Priddy LB, Lim JJ, Koob TJ. Dehydrated Human Amnion/Chorion Membrane (dHACM) Allografts as a Therapy for Orthopedic Tissue Repair. Techniques in Orthopaedics. 2017. DOI: 10.1097/BTO.0000000000000229.

AmnioCord® & EpiCord®

Bullard JD, Lei J, Lim JJ, Massee M, Fallon AM, Koob TJ. Evaluation of dehydrated human umbilical cord biological properties for wound care and soft tissue healing. Journal of Biomedical Materials Research Part B: Applied Biomaterials. 2018. DOI: 10.1002/jbm.b.34196.

CollaFix®

Qiu Y, Lei J, Koob TJ, Temenoff JS. “Cyclic tension promotes fibroblastic differentiation of human MSCs cultured on collagen-fibre scaffolds.” Journal of Tissue Engineering and Regenerative Medicine. 2014; doi: 10.1002/term.1880